Oncologists Hold Advanced Options in Treatment for Mesothelioma, Even if Prognosis Looks Desperate
Oncologists and other cancer doctors determine what course of treatment to administer to each patient. The options are endless. There are no standard treatment option for peritoneal mesothelioma victims. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.
While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Treatments for cancer are traditionally surgery (taking out the tumor and surrounding tissue), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) Each one of these methods have problems. Patients with mesothelioma have not responded well to traditional radiation therapy. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
Surgery takes out the mesothelial cancerous tissue around the tumor. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different mixtures of these drugs have not been successful. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.
The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
